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All about COPD

COPD (Chronic Obstructive Pulmonary Disease) is a very common condition in the UK. It accounts for more time off work than any other illness. COPD is a general term which includes the conditions Chronic Bronchitis and Emphysema. What do the medical words mean?

 * Chronic means ongoing and persistent. 
 * Pulmonary means 'affecting the lungs'.
 * Bronchitis means inflammation of the airways of the lungs (the breathing tubes).
 * Emphysema is damage to the smaller airways of the lungs.

Either chronic bronchitis or emphysema can cause a obstruction (narrowing) of the airways. In many people a degree of both chronic bronchitis and emphysema are present. This is why the general term COPD is used to describe airways that are narrowed due to chronic bronchitis, emphysema or a combination of them both. What causes COPD?

The lining of the airways becomes inflamed and damaged. Smoking causes this inflammation and damage in the vast majority of people with COPD. There is no doubt about this. About 3 in 20 one-pack-per-day and 1 in 4 two-pack-per-day smokers develop COPD if they continue smoking. Air pollution and polluted work conditions may play a part or make the disease worse. However, people who have never smoked rarely develop COPD. What are the symptoms of COPD?

 * Cough - this is often the first symptom to develop. It is usually productive with phlegm (sputum). It tends to come and go at first and then gradually becomes more persistent (chronic). The cough is often thought of as a 'smokers cough' in the early stages of the disease. It is when the breathlessness begins that people often become concerned.
 * Breathlessness and wheeze - these may only be noticed after exertion at first. As time goes by breathlessness may develop even when resting. The decline in the breathing can be very gradual over a number of years if smoking continues. Eventually it can become quite serious and distressing in some people.
 * Sputum - the damaged airways produce a lot more mucus than normal which forms sputum. People with COPD often cough up a lot of sputum each day.
 * Chest infections - people with COPD are prone to chest infections. Wheezing with cough and breathlessness may become worse than usual when chest infections occur. There is often an increased amount of sputum (phlegm) which may turn yellow or green.

What is the progression and outlook of COPD?

The symptoms described above usually take years to progress. Symptoms usually begin in people aged over 40 who have smoked for 20 years or more. Typically, there is a very gradual decline over several years from an irritating 'smokers cough' to increasing breathlessness. There may at first be the occasional chest infection. Chest infections may then become more frequent as time goes by. If smoking continues, COPD usually becomes worse over time. Some people eventually become breathless and wheezy all the time. In some people the narrowed airways and increased breathlessness reduce the amount of oxygen passed from the lungs into the bloodstream. This may affect the heart which needs a good oxygen supply and cause heart failure. About 25,000 people die each year in England and Wales from the end stages of COPD. For many of these people there are several years of ill health and poor quality of life before death. How can the course of the COPD be altered?

Stop smoking - this cannot be stressed enough. Stopping smoking will not reverse any damage already done to the lungs but it will greatly help to stop the disease getting worse. If this is done early on in the disease it will make a huge difference. When the condition first develops and symptoms are mild, some people deceive themselves (and others) and say that they have just a 'smokers cough'. If smoking is stopped at this stage it is unlikely that COPD will progress to a severe illness. However, it is never too late to stop at any stage of the disease. Even people with fairly advanced COPD will benefit and prevent further progression of the disease.

Some people do give up smoking for a while but find their cough becomes worse. This often happens as the lining of the airways 'come back to life'. Resist the temptation to restart smoking to ease the cough. Any increase in cough after stopping smoking usually settles in a few weeks. What are the treatments for COPD? 
* Inhalers that open the airways (bronchodilators) are often prescribed. These work by relaxing the muscles in the airways to try and open up them up as wide as possible. These include beta agonist inhalers such as salbutamol and terbutaline and anticholinergic inhalers such as ipratropium or atrovent. Inhalers work well for some people with COPD. In other people they may not work so well because of the damaged and thickened airways. Some people with mild or intermittent symptoms may only need an inhaler 'as required' for when breathlessness or wheeze occur. Some people need to use inhalers regularly. The different types of inhalers work in different ways and a combination of two inhalers may be beneficial for some people. 
* Steroid inhalers are useful for some people in addition to bronchodilator inhalers. Steroid medication 'dampens down' inflammation. To see if a steroid inhaler will help, a short course of steroid tablets may be prescribed. An improvement in symptoms or in breathing tests after a course of steroid tablets shows that a steroid inhaler may help. It is people with COPD who have an 'asthma tendency' who benefit from steroid inhalers most.
 * Bronchodilator tablets which contain similar medicines that are in inhalers are sometimes prescribed. Inhalers are usually better and they also cause less side effects. However, some people find inhalers difficult and tablets may be an alternative. 
* Steroid tablets are sometimes prescribed for a short course when very wheezy and breathless (often during a chest infection). They help by damping down the extra inflammation in the airways caused by infections. 
* Antibiotics - chest infections are more common in people with COPD. These may be treated with short courses of antibiotics. 
* Oxygen - in people with severe symptoms, regular oxygen may help.

What can I do to help? 
* Get immunised - a yearly 'flu jab' each autumn protects against possible chest damage from influenza. Immunisation against pneumococcus (a germ that can cause serious chest infections) may also be advised. This is one injection and not needed yearly like the 'flu jab'. 
* Keep fit - people with COPD who exercise regularly tend to improve their breathing capacity. Any regular exercise is good. A daily walk is a good start for people not used to exercise. 
* Lose weight - if overweight. Carrying extra weight can make breathlessness worse.

In summary 
* For most people, COPD is caused by smoking. 
* Many people with mild COPD slowly become worse because they continue to smoke. 
* If smoking is stopped, the progression of COPD can be slowed drastically. A much better quality of life can be expected for the coming years than if smoking were to continue. 
* The earlier smoking stops, the better. However, it is never too late to stop to have a beneficial effect on the disease. * Treatments with inhalers may help with symptoms but no treatment can reverse the damage to the airways. 
* Flare-ups of symptoms and chest infections may be helped by short courses of steroids and/or antibiotics.

Further help and information

British Lung Foundation, 78 Hatton Garden, London, EC1N 8JR Tel: 0171 831 5831 Web:

www.lunguk.org/index.htm